FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
1. Name and Address of Reporting Person*
Shell William

(Last)(First)(Middle)
C/O TARGETED MEDICAL PHARMA, INC., 2980 BEVERLY GLEN CIRCLE, SUITE 301

(Street)
LOS ANGELESCA90077

(City)(State)(Zip)
2. Issuer Name and Ticker or Trading Symbol
Targeted Medical Pharma, Inc. [TRGM]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
XDirectorX10% Owner
XOfficer (give title below)Other (specify below)
CEO & Chief Scientific Officer
3. Date of Earliest Transaction (Month/Day/Year)
11/11/2013
4. If Amendment, Date of Original Filed (Month/Day/Year)
6. Individual or Joint/Group Filing (Check Applicable Line)
Form filed by One Reporting Person
XForm filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
CodeVAmount(A) or (D)Price
Common Stock, $.001 par value per share 11/11/2013 G  24,999 D$ 0 5,345,055 I By trust (1)
Common Stock, $.001 par value per share 11/11/2013 W  98,965 A$ 0 819,764 I By trust (2)
Common Stock, $.001 par value per share 11/11/2013 W  130,709 A$ 0 3,553,457 I By trust (3)
Common Stock, $.001 par value per share 11/11/2013 W  229,674 D$ 0 5,115,381 I By trust (1)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
1. Name and Address of Reporting Person*
Shell William

(Last)(First)(Middle)
C/O TARGETED MEDICAL PHARMA, INC., 2980 BEVERLY GLEN CIRCLE, SUITE 301

(Street)
LOS ANGELESCA90077

(City)(State)(Zip)
1. Name and Address of Reporting Person*
William Shell Survivor's Trust

(Last)(First)(Middle)
3048 NICADA DRIVE

(Street)
LOS ANGELESCA90077

(City)(State)(Zip)
1. Name and Address of Reporting Person*
Elizabeth Charuvastra Marital Trust

(Last)(First)(Middle)
3048 NICADA DRIVE

(Street)
LOS ANGELESCA90077

(City)(State)(Zip)
Explanation of Responses:
1. Common stock held by William Shell Survivor's Trust.
2. Common stock held by Elizabeth Charuvastra Exemption Trust. William E. Shell is filing on behalf of the Elizabeth Charuvastra Exemption Trust and disclaims any and all pecuniary interest in the Elizabeth Charuvastra Exemption Trust.
3. Common stock held by Elizabeth Charuvastra Marital Trust
/s/ William E. Shell11/20/2013
William Shell Survivor's Trust, by /s/ William E. Shell11/20/2013
Elizabeth Charuvastra Marital Trust, by /s/ William E. Shell11/20/2013
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
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