Unassociated Document
Washington, D.C. 20549

FORM 12b-25


(Check One):
x Form 10-K   o Form 20-F   o Form 11-K   o Form 10-Q   o Form 10-D   o Form N-SAR   oForm N-CSR

For Period Ended: December 31, 2010

o Transition Report on Form 10-K
o Transition Report on Form 20-F
o Transition Report on Form 11-K
o Transition Report on Form 10-Q
o Transition Report on Form N-SAR
For the Transition Period Ended: __________

Nothing in this form shall be construed to imply that the Commission has verified any information contained herein.

If the notification relates to a portion of the filing checked above, identify the Item(s) to which the notification relates: ________________________


Full Name of Registrant

See Table of Additional Subsidiary Guarantor Registrants

2980 Beverly Glen Circle, Suite 301
Address of Principal Executive Office (Street and Number)

Los Angeles, California 90077
City, State and Zip Code

PART II -- RULES 12b-25(b) AND (c)

If the subject report could not be filed without unreasonable effort or expense and the registrant seeks relief pursuant to Rule 12b-25(b), the following should be completed. (Check box if appropriate.) x

(a) The reasons described in reasonable detail in Part III of this form could not be eliminated without unreasonable effort or expense;
(b) The subject annual report, semi-annual report, transition report on Form 10-K, Form 20-F, Form 11-K, Form N-SAR or Form N-CSR, or portion thereof, will be filed on or before the 15th calendar day following the prescribed due date; or the subject quarterly report or transition report on Form 10-Q, or subject distribution repot on Form 10-D, or portion thereof, will be filed on or before the fifth calendar day following the prescribed due date; and
(c) The accountant's statement or other exhibit required by Rule 12b-25(c) has been attached if applicable.


State below in reasonable detail the reasons why Forms 10-K, 20-F, 11-K, 10-Q, N-SAR, N-CSR, or the transition report or portion thereof, could not be filed within the prescribed time period.

We are unable to file our Form 10-K for the period ended December 31, 2010 within the prescribed period because we have not completed all our accounting and required disclosures due to the comments received from the Securities and Exchange Commission on the Company’s pending registration statement on Form S-1, which comments impact the required disclosures in our Form 10-K.


(1)   Name and telephone number of person to contact in regard to this notification
Steve B. Warnecke   (310) 474-9809
(Name)   (Area Code) (Telephone Number)

(2)   Have all other periodic reports required under Section 13 or 15(d) of the Securities Exchange Act of 1934 or Section 30 of the Investment Company Act of 1940 during the preceding 12 months or for such shorter period that the registrant was required to file such report(s) been filed? If answer is no, identify report(s).
x Yes o No

(3)   Is it anticipated that any significant change in results of operations for the corresponding period for the last fiscal year will be reflected by the earnings statements to be included in the subject report or portion thereof?
x Yes o No

If so, attach an explanation of the anticipated change, both narratively and quantitatively, and, if appropriate, state the reasons why a reasonable estimate of the results cannot be made.

Pursuant to an Agreement and Plan of Reorganization (the “Merger Agreement”), by and among our predecessor, AFH Acquisition III, Inc. (“AFH”), TMP Merger Sub, Inc. (“TMP Merger Sub”), AFH Merger Sub, Inc. (“AFH Merger Sub”), AFH Holding and Advisory, LLC (“AFH Advisory”), Targeted Medical Pharma, Inc. (“Old TMP”), William E. Shell, MD, Elizabeth Charuvastra and Kim Giffoni, on January 31, 2010, TMP Merger Sub merged (the “TMP Merger”) with and into Old TMP with Old TMP continuing as the surviving entity (we are the surviving entity of the TMP Merger). Immediately after the TMP Merger, AFH merged (the “AFH Merger” and, together with the TMP Merger, the “Reorganization”) with and into AFH Merger Sub with AFH continuing as the surviving entity. As a result of the Reorganization, the Company will report on the financial condition and results of operation of the business following the consummation of the Reorganization.  The Company expects revenue and net income form 2010 to be substantially greater than 2009.

Targeted Medical Pharma, Inc.
(Name of Registrant as Specified in Charter)

has caused this notification to be signed on its behalf by the undersigned hereunto duly authorized.
Date: March 31, 2011   TARGETED MEDICAL PHARMA, INC.  
  /s/ William E. Shell, MD  
    William E. Shell, MD  
    Chief Executive Officer