FORM 3UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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1. Name and Address of Reporting Person*
Silver David Samuel

(Last)(First)(Middle)
C/O TARGETED MEDICAL PHARMA, INC., 2980 BEVERLY GLEN CIRCLE, SUITE 301

(Street)
LOS ANGELESCA90077

(City)(State)(Zip)
2. Date of Event Requiring Statement (Month/Day/Year)
10/17/2011
3. Issuer Name and Ticker or Trading Symbol
Targeted Medical Pharma, Inc. [NONE]
4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
XDirector10% Owner
Officer (give title below)Other (specify below)
5. If Amendment, Date of Original Filed (Month/Day/Year)
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
Table I - Non-Derivative Securities Beneficially Owned
1. Title of Security (Instr. 4) 2. Amount of Securities Owned (Instr. 4) 3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5) 4. Nature of Indirect Beneficial Ownership (Instr. 5)
Common Stock 284,623
I
By Silver Family Trust
Common Stock 8,874
I
By daughter (1)
Common Stock 8,874
I
By son (1)
Common Stock 8,874
I
By son (1)
Common Stock 8,874
I
By son (1)
Common Stock 8,874
I
By son (1)
Common Stock 8,874
I
By son (1)
Table II - Derivative Securities Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 4) 2. Date Exercisable and Expiration Date (Month/Day/Year) 3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)4. Conversion or Excercise Price of Derivative Security 5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5) 6. Nature of Indirect Beneficial Ownership (Instr. 5)
Date ExercisableExpiration DateTitleAmount or Number of Shares
Options to Purchase Common Stock  (2) (2) Common Stock 177,469 $ 3.38 D  
Options to Purchase Common Stock  (3) (3) Common Stock 275,077 $ 0.77 D  
Explanation of Responses:
1. Dr. Silver retains investment and voting control over these shares. Dr. Silver disclaims beneficial ownership of these shares to the extent of his pecuniary interest therein.
2. The option became exercisable as to 59,157 of the shares on March 20, 2010. The option became exercisable as to an additional 59,156 shares on March 1, 2011. The option becomes available for the remaining 59,156 shares on March 1, 2012. The expiration date for these options is 10 years after they vest, so the expiration dates are March 20, 2020, March 1, 2021, and March 1, 2022, respectively.
3. The option became exercisable as to 91,693 of the shares on May 1, 2007. The option became exercisable as to an additional 91,692 shares on May 1, 2008. The option became exercisable as to the remaining 91,692 shares on May 1, 2009. The expiration date for these options is 10 years after they vest, so the expiration dates are May 1, 2017, May 1, 2018, and May 1, 2019, respectively.
/s/ David S. Silver10/28/2011
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
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