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                                                           August 21, 2024

Jeffrey Frelick
Chief Executive Officer
Bone Biologics Corp
2 Burlington Woods Drive
Suite 100
Burlington, MA 01803

        Re: Bone Biologics Corp
            Registration Statement on Form S-3
            Filed August 12, 2024
            File No. 333-281494
Dear Jeffrey Frelick:

       This is to advise you that we have not reviewed and will not review your
registration
statement.

       Please refer to Rules 460 and 461 regarding requests for acceleration.
We remind you that
the company and its management are responsible for the accuracy and adequacy of
their
disclosures, notwithstanding any review, comments, action or absence of action
by the staff.

        Please contact Robert Augustin at 202-551-8483 with any questions.


                                                           Sincerely,

                                                           Division of
Corporation Finance
                                                           Office of Industrial
Applications and
                                                           Services
cc:    Alexander R. McClean
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